Planning for gene therapy

Planning for gene therapy

In spite of some setbacks, gene therapy trials continue, while the UK government is putting in place plans to bring the potential power of genetics into mainstream public heathcare through its National Health Service.

A method for standardizing intensity modulated radiation therapy planning optimization for nasopharyngeal carcinoma

Background: To investigate a method for standardizing intensity modulated radiation therapy (IMRT) optimization for nasopharyngeal carcinoma (NPC), in order to reduce the influence of subjective factors. Materials and Methods: This study is based on example IMRT plans for NPC, which were randomly divided into data acquisition and data verification groups. Organs at risk (OARs) were analyzed for...

ژن درمانی Gene Therapy

gene expression profiling for cancer targeted therapy

background : lung cancer is still the leading cause of cancer- related deaths and most of themâ  are normally diagnosed in late stages, so there is an urgent need to establish reliable tools for the identification at early stages of the disease. in this study, we use an eleven gene signature test to examine lung biopsy specimens for diagnostic, prognostic & therapeutic purposes. methods : bronc...

Iterative Approach for Automatic Beam Angle Selection in Intensity Modulated Radiation Therapy Planning

Introduction: Beam-angle optimization (BAO) is a computationally intensive problem for a number of reasons. First, the search space of the solutions is huge, requiring enumeration of all possible beam orientation combinations. For example, when choosing 4 angles out of 36 candidate beam angles, C36 = 58905 possible combinations exist.  Second, any change in a   beam 4 config...